Are there any cosmic horror comic books that blend other genres effectively?

Yes, many cosmic horror comic books successfully blend genres. For instance, 'Saga' by Brian K. Vaughan and Fiona Staples, while primarily a space opera, often incorporates elements of cosmic dread through its depiction of vast, ancient forces and the existential struggles of its characters. 'The Wicked + The Divine' by Kieron Gillen and Jamie McKelvie plays with cosmic themes through its exploration of gods and their cyclical destruction and rebirth, hinting at forces beyond mortal understanding.