What advanced steps can I take to debug persistent .NET Framework unhandled exceptions?

For persistent issues, you can configure .NET Framework tracing (if the application supports it via configuration files like `app.config`), use tools like Process Monitor (ProcMon) to log file and registry access that might indicate permission issues or missing files, or collect a crash dump using Task Manager or ProcDump when the error occurs. Analyzing these dumps, though complex, can provide detailed insights into the exception's origin, often requiring specialized debugging tools like WinDbg.