How does the 'Optimus Prime' series connect to the larger IDW Transformers universe?

The 'Optimus Prime' series serves as a direct continuation of the 'More Than Meets The Eye' and 'Robots in Disguise' storylines. It builds upon the established lore and character arcs from those series, showing the consequences of the Unicron battles and the shifting political landscape of Cybertron. It eventually leads into the 'Revolution' and 'Destiny' events, culminating in the reboot of the IDW universe.